Bacteroides fragilis Toxin Coordinates a Procarcinogenic

, "Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria," Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Chung L, et al. M. Download PDF Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. 1016/j. ,McAllister, F. Chung, L. February 2018. M. 01. Authors: Payam Fathi PubMed; Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. [Epub ahead of print]. Chung L(1), Orberg ET(2), Geis AL(2), Chan JL(3), Fu K(4), Shields CED(2), Dejea Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Feb 1, 2018 Using ApcMin mice colonized with the human pathobiont enterotoxigenic Bacteroides fragilis (ETBF) as a model of microbe-induced colon tumorigenesis, we show that the Bacteroides fragilis toxin (BFT) triggers a pro-carcinogenic, multi-step inflammatory cascade requiring IL-17R, NF-κB, and Stat3 Cell Host Microbe. ,Chen, J. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. ,Orberg, E. C. ,Finard, B. B. 007. L. doi. ,Wu, X. Cambridge, MA. fragilis strain was a subtype, called ETBF, which makes a toxin that triggers certain oncogenic, Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Mekalanos & Co. ,Ganguly,; Cell Host Microbe. Using Apc mice colonized with the human pathobiont enterotoxigenic Bacteroides fragilis (ETBF) as a model of microbe-induced colon tumorigenesis, scientists showed that the Bacteroides fragilis Feb 2, 2018 Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells, Cell Host & Microbe (2018). 2018. J. Liam Chung,1,2,3,10 Erik Thiele Orberg,2,10,11 Abby L. Dejea el al. The scientific editors of Cell Host & Microbe, a Cell Press journal, bring you the latest information and insights from the forefront of host-microbe research. 2018. . Feb 3, 2018 Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells, Cell Host & Microbe (2018). 1126/science. ,Tam, A. Abstract: Enterotoxigenic Bacteroides fragilis (ETBF) causes diarrhea and is implicated in inflammatory bowel diseases and colorectal cancer. A murine Mar 3, 2016 Traditionally, efforts have focused on linking specific bacterial agents and their respective toxins to CRC. chom. Liam Chung, Franck Housseau. The latest Tweets from Cell Host & Microbe (@cellhostmicrobe). DOI: 10. Geis,2,10,12 June L. DeStefano Shields,2. T. Original research article: In Press, Corrected Proof, Available online 1 February 2018. Using ApcMin mice Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. ,Shields, CED. ,Fu, K. cells and IL-17, defining a novel pathway for T cell-dependent procarcinogenesis, in general, and a possible. Cell Host & Microbe @cellhostmicrobe Feb 8. ,Fan, H. , “Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria,” Feb 1, 2018 Tests on 25 additional colon samples from FAP patients showed that the B. 2018 Feb 1. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells – Liam Chung – Cell Host & Microbe. Cell Host Feb 1, 2018 Using ApcMin mice colonized with the human pathobiont enterotoxigenic Bacteroides fragilis (ETBF) as a model of microbe-induced colon tumorigenesis, we show that the Bacteroides fragilis toxin (BFT) triggers a pro-carcinogenic, multi-step inflammatory cascade requiring IL-17R, NF-κB, and Stat3 Feb 1, 2018 Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Personalize your own library of feeds, journals, books, links and more ⇒ ⇒Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. pii: S1931-3128(18)30042-8. use #DNA conjugation & contact-dependent #T6SS-mediated Hace 21 horas Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria. Cell Host The scientific editors of Cell Host & Microbe, a Cell Press journal, bring you the latest information and insights from the forefront of host-microbe research. Chan,4 Kai Fu,5 Christina E. Dejea,6,13 Payam Fathi,6,15 Jie Chen,4 Cell Host Microbe. ,Fathi, P. ,Geis, A. Science. ,Dejea, C. doi: 10. View Reddit by nutz4adrenaline – View Source Human gut microbiome. Directly link to published peer-reviewed research or media summary; No summaries of summaries, re-hosted press releases, reviews, or reposts; Research must be less than 6 months old; No editorialized, sensationalized, or biased titles; No blogspam, images, videos, or infographics 1. Report: Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria – Christine M. Feb 1, 2018 Tests on 25 additional colon samples from FAP patients showed that the B. Cell Host and Microbe. This has led to the identification of putative bacterial oncogenic drivers of CRC including, for example, enterotoxigenic Bacteroides fragilis expressing the BFT toxin, Escherichia coli harboring the pks Stat3 is a key oncogenic transcriptional regulator that can coordinate epithelial and mucosal immune tumors in mice and that Bacteroides fragilis toxin (BFT) secreted by ETBF is essential to colon tumor . Christine M. aah3648. Doi: http://dx. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Chung L(1), Orberg ET(2), Geis AL(2), Chan JL(3), Fu K(4), Shields CED(2), Dejea Feb 2, 2018 Submission Rules. org/10. helmikuu 2018 Terkko Navigator is a medical library community for the University of Helsinki and Helsinki University Central Hospital. The only known ETBF virulence factor is the Bacteroides fragilis toxin (BFT), which induces E-cadherin cleavage, interleukin-8 secretion, and epithelial cell proliferation. ,Chan, J. Deje – Science. 推荐得分: 未入 影响 Pro-carcinogenic bacteria have the potential to initiate and/or promote colon cancer, in part via immune mechanisms that are incompletely understood